Habitat:

The plant is mostly found in temperate Himalayas from Kashmir to Bhutan and in Khasia hills at 1500 meter altitude.

Morphology Description (Habit):

A perennial herb, up to 35 cm tall. Root-stock very stout. Stems short, thick, fleshy, and procumbent. Leaves few, spreading, 4-11 x 3-10 cm, glabrous or hirsute, sub-orbicular to orbicular or broadly obovate, base cordate or sometimes rounded, apex rounded or sometimes abruptly acuminate; margin entire to occasionally denticulate at top, fringed with short stiff hairs, both surfaces hairy, becoming almost hairless in age. Petiole 1-2(-5) cm long, glabrous or hirsute, sheathing at the base. Inflorescence a one sided raceme or corymbose, often subtended by an ovate leafy bract; bract glabrous or sparsely ciliate; scape and inflorescence greenish or pink tinged. Peduncle up to 10 cm long; flowers pink to purplish, pedicellate. Sepals 7 mm long, oblong. Petals 10 x 4 mm, unguiculate, limb orbicular. Filaments 1 cm long, pink to red. Carpels 2. Styles 7 mm long. Carpels and styles green or pinkish. Flowering tem flexible, leafless, 10-25 cm. long. Capsule 13 x 6 mm, including styles. Seeds elongated, 1 mm long, brown, minutely tuberculate.

Rhizome, solid, barrel shaped, cylindrical, 1.5-3 cm long and 1-2 cm in diameter with small roots, ridges, furrows and root scars distinct, transversely cut surface shows outer ring of brown coloured cork, short middle cortex, vascular bundles and large central pith, odour, aromatic, taste, astringent.1

Parts Used:

Root (Rhizome)

Phytochemistry:

Bergenin, Tannic acid, Gallic acid, Stigmesterol, β-Sitosterol, catechin, (+)-Afzelechin, 1, 8-cineole, Isovalaric acid, (+)-(6S)-parasorbic acid, Arbutin, Phytol, Caryophyllene, Damascenone, β-eudesmol, 3-methyl-2-buten-1-ol, (Z)-asarone, Terpinen-4-ol, Paashaanolactone.1

Pharmacological Actions:

The primary pharmacological actions of this herb are summarized as under:

Endocrinal System: 

i. Exhibits α-glucosidase inhibitory activity.2

Urinary System: 

i. The antiurolithic activity in Bergenia ligulata mediated possibly through CaC(2)O(4) crystal inhibition, diuretic, hypermagneseuric and antioxidant effects.3

ii. Exhibits diuretic activity

Others: 

i. Bergenin and 11-O-galloylbergenin, isolated from this herb showed potent antioxidant activity.4

ii. Possesses anti-inflammatory and antibacterial activities.5

Indications:

Urinary tract calculi

Urinary tract infections

References:

1. Verma P, Joshi BC, Negi N. A review on therapeutic potentials of Bergenia ligulata wall. PharmaTutor.

2. Kashima Y, Yamaki H, Suzuki T, Miyazawa M. Structure-activity relationships of bergenin derivatives effect on α-glucosidase inhibition. J Enzyme Inhib Med Chem. 2013 Dec;28(6):1162-70.

3. Bashir S, Gilani AH. Antiurolithic effect of Bergenia ligulata rhizome: an explanation of the underlying mechanisms. J Ethnopharmacol. 2009 Feb 25;122(1):106-16.

4. Uddin G, Sadat A, Siddiqui BS. Comparative antioxidant and antiplasmodial activities of 11-O-galloylbergenin and bergenin isolated from Bergenia ligulata. Trop Biomed. 2014 Mar;31(1):143-8.

5. Tehseen Sajad, Afzal Zargar, Tasleem Ahmad, et al. Antibacterial and Anti-inflammatory Potential Bergenia ligulata. American Journal of Bimedical Sciences. 2010; 2(4): 313-321.

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Product Range:

Eurinex Capsule